I don't really understand what the difference is between a rune and an infusion. The wiki for the game says:

Inscriptions come in two flavors: runes and infusions. Runes are magical glyphs drawn on the body like temporary tattoos. Infusions are natural substances smeared/attached to the body, like nicotine patches.

That doesn't really clear it up for me. I'm assuming there is a mechanical difference and not just a thematic difference?

1 Answer

It boils down to the power source, as described in the flavor text. Runes are arcane, and therefore suppressed by antimagic, and not usable by Zigur followers. Infusions are natural, and cannot be used by undead characters.

2